在低氧条件下耐力运动对胃排空率和肠道细胞损伤的影响
Sayaka Nomura1, Daichi Sumi2,3, Haruna Nagatsuka1
1Graduate School of Sport and Health Science, Ritsumeikan University, 1-1-1, Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.
European journal of applied physiology
|October 25, 2024
概括
在低氧条件下的耐力运动减缓了胃空气的排泄,并增加了与正常条件相比的恶心. 然而,肠道细胞损伤标志物在两个运动条件之间没有差异.
科学领域:
- 运动生理学 运动生理学
- 胃肠道生理学 胃肠道生理学
- 环境生理学环境生理学
背景情况:
- 耐力运动会影响胃肠道功能.
- 缺氧是一种氧气供应减少的状态,可能会进一步改变运动期间的生理反应.
研究的目的:
- 为了研究缺氧与诺莫西克耐力运动对胃排空率的影响.
- 在低氧和正常氧条件下评估运动诱导的肠细胞损伤.
主要方法:
- 11名健康的男性在低氧 (FiO2: 14.5%) 或正常氧 (FiO2: 20.9%) 条件下以70%的最大运行速度完成了60分钟的跑步机跑步.
- 用13C-酸盐呼吸试验测量了胃空气的速度.
- 血肠脂肪酸结合蛋白 (I-FABP) 被分析为肠细胞损伤的标记物.
主要成果:
- 在低氧条件下 (45.5分钟) 与正常条件下 (38.5分钟) 相比,胃排空,以最大13C排泄时间表示,在低氧条件下显著延迟 (45.5分钟).
- 恶心得分仅在低氧试验中在运动后显著增加.
- 血I-FABP度和甲基醇胺水平在低毒和正常毒试验之间没有显著差异.
结论:
- 在低氧条件下的耐力运动会损害胃空气,并加剧恶心,相比于在正常条件下的相同相对强度的运动.
- 尽管胃功能受损,但这种强度的低氧运动似乎不会比正常运动更严重地损害肠道细胞.
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