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Updated: Jun 17, 2026

Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography
04:24

Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography

Published on: November 22, 2017

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毒性和母体暴露:对后代大鼠膜骨变化的表征

Matheus Ferreira Lima Rodrigues1, Deiweson Souza-Monteiro1, Rayssa Maitê Farias Nazário1

  • 1Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, 01 Augusto Corrêa Street, Guamá, Belém, PA, Zip Code 66075-110, Brazil.

Biological trace element research
|October 25, 2024
PubMed
概括

孕妇在怀孕和哺乳期间接触会损害后代的气膜骨发育. 这项研究表明,大鼠暴露于酸会损害骨结构和组成,影响骨健康.

关键词:
气囊骨骨头的骨领导 领导 领导 领导 领导微型CT技术的使用他们有后代,有后代的后代.红色的皮克罗西里乌斯红色拉曼光谱法 拉曼光谱法

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...