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在瘤突变负担高的质母细胞瘤患者中 pembrolizumab 的疗效:一个案例研究和对精确瘤学的影响

Akihiro Nishiyama1, Shigeki Sato1, Hiroyuki Sakaguchi1

  • 1Department of Medical Oncology, Kanazawa University Hospital, Kanazawa, Japan.

Cancer science
|October 25, 2024
PubMed
概括

一名质母细胞瘤患者患有高瘤突变负担和不匹配修复缺陷,对免疫检查点抑制剂 pembrolizumab 反应良好. 这一案例突显了精确瘤学的精确性.

关键词:
质母细胞瘤 (glioblastoma) 是一种不匹配 维修 缺陷 缺陷这就是Pembrolizumab.精确瘤学 精确瘤学瘤突变负担 瘤突变负担

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