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Updated: Jun 9, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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通过整合p53动态和修改,对基因表达的时间调节

Dan Lu1, Marjan Faizi1, Bryon Drown2

  • 1Department of Systems Biology, Blavatnik Institute at Harvard Medical School, Boston, MA 02115, USA.

Science advances
|October 25, 2024
PubMed
概括

转录因子p53,DNA损伤反应的关键调节者,在表达脉冲之间改变其乙化状态. 这种修改动态改变基因表达程序,使细胞修复过程的时间协调.

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