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用病毒和人工带进行定向依赖的CD45抑制

Marta T Borowska1, Liu D Liu1, Nathanael A Caveney1

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94063, USA.

Science immunology
|October 25, 2024
PubMed
概括

腺病毒E3/49K蛋白与CD45 (细胞表面酸酶) 结合,抑制T细胞信号传递. 这种相互作用激发了工程带,通过控制CD45二分化来调节T细胞激活.

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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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