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Updated: Jun 9, 2025

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain
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A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

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工程外膜囊泡作为纳米化免疫细胞参与者,用于增强固体瘤免疫治疗.

Jianan Sun1, Liu Tan1, Bang-Ce Ye2

  • 1Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, P. R. China.

ACS nano
|October 25, 2024
PubMed
概括

研究人员开发了一种基于OMV的新型免疫细胞吸引剂 (OMV-NICE),用于固体瘤免疫治疗. 这种双重向的方法增强了免疫细胞的参与,并在临床前模型中表现出卓越的抗瘤活性.

关键词:
在SpyCatcher/SnoopCatcher中使用.免疫细胞参与参与者纳米体是一个纳米体.在外膜囊泡中,外膜囊泡瘤免疫疗法 免疫疗法

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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