边界胎儿生长与进展的关联与胎儿生长限制
Baillie A Bronner1, Monique Holod2, Margaret Schermerhorn3
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mountain Area Health Education Center, Asheville, North Carolina.
American journal of perinatology
|October 25, 2024
概括
边界胎儿生长,估计胎儿体重在10至15个百分点之间,增加胎儿生长限制 (FGR) 的风险,并提供一个小的妊娠年龄 (SGA) 新生儿. 推对这些患者进行随访产前生长评估.
科学领域:
- 产科和妇科 产科和妇科
- 胎儿医学 胎儿医学
- 新生儿健康 新生儿健康
背景情况:
- 估计胎儿体重 (EFW) 评估在怀孕监测中至关重要.
- 边界胎儿生长,定义为EFW在第10和第15百分位之间,需要进一步调查其临床意义.
- 识别有不良结果风险的胎儿对于及时干预至关重要.
研究的目的:
- 在解剖扫描中确定边界胎儿生长是否与胎儿生长限制 (FGR) 的进展有关.
- 评估边缘胎儿生长和妊娠年龄小 (SGA) 新生儿的分娩之间的关联.
- 评估边缘胎儿生长和新生儿重症监护室 (NICU) 住院之间的关系.
主要方法:
- 无卵性妊娠结果研究的二次分析:监测即将成为母亲的数据 (nuMom2b).
- 怀孕与边缘胎儿生长 (EFW第10至15百分位) 与正常生长 (EFW>15百分位) 的比较.
- 多变量分析根据主要的人口和临床因素进行调整,以评估初级和二级结果.
主要成果:
- 在随后的扫描中,边界胎儿生长显著增加了发展FGR的几率 (aOR = 6.68).
- 患有边缘胎儿生长的患者更有可能分娩SGA新生儿 (6.14%vs2.67%).
- 两组之间没有观察到NICU入院的显著差异.
结论:
- 在解剖扫描中诊断出边缘胎儿生长与FGR进展和SGA新生儿分娩的风险更高有关.
- 胎儿EFW在10至15百分位之间,需要增加临床关注.
- 建议对怀孕中被发现有边缘胎儿生长的孕妇进行产前生长评估.
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