在COPD的诊断环境中,患者的特征和死亡率
Sebastian Tristan Ehlert Buchardt1, Ulla Møller Weinreich2, Filip Lyng Lindgren3
1Department of Respiratory Diseases, Aalborg University Hospital, Denmark.
Respiratory medicine
|October 25, 2024
概括
慢性阻塞性肺病 (COPD) 的晚期诊断增加了死亡风险. 在COPD第一次急性恶化之前在初级保健中诊断的患者 (AECOPD) 与入院期间诊断的患者相比,一年的存活率更好.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 许多患有慢性阻塞性肺病 (COPD) 的患者面临延迟诊断,通常只有在COPD (AECOPD) 首次急性恶化时才被发现.
- AECOPD是COPD患者死亡率增加的重要危险因素.
研究的目的:
- 在COPD的不同诊断设置中调查患者特征和相关死亡率.
- 为了比较COPD患者在初级保健诊断的结果与医院设置.
主要方法:
- 丹麦的一项全国性研究分析了2010年至2018年期间107,023名首次COPD相关医院接触的患者.
- 患者根据诊断环境进行分类:初级保健,医院门诊或住院.
- 使用多变量逻辑回归来分析患者特征和死亡率.
主要成果:
- 大多数患者 (75.7%) 在初级保健中被诊断出患病 (平均年龄为63岁).
- 在入院期间诊断的患者 (13.7%) 较老 (平均年龄73岁),主要是男性,并患有更多的并发症.
- 住院期间的诊断,特别是由于AECOPD,与初级保健诊断相比,增加了24%的一年死亡风险.
结论:
- 在医院诊断的COPD患者往往是年长,男性,并具有更高的并发症负担.
- 在初级保健中,在第一个AECOPD之前,早期诊断与COPD患者的一年生存率的改善有关.
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