计算流体动力学模拟母体血流在未破裂的A1动脉瘤栓塞中的应用
Gangqin Xu1, Kun Zhang1, Dongyang Cai1
1Division of Interventional Therapy Center, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital, Cerebrovascular Division of Interventional Therapy Center, Zhengzhou University People's Hospital, Henan Provincial Neurointerventional Engineering Research Center, Zhengzhou, China.
World neurosurgery
|October 25, 2024
概括
计算流体动力学 (CFD) 模拟引导的微导管塑造改善了前脑动脉动脉瘤的栓塞. 这种技术是安全和有效的复杂解剖导航,导致成功的动脉瘤堵塞.
科学领域:
- 神经外科 神经外科
- 干预性放射学 干预性放射学
- 生物医学工程 生物医学工程
背景情况:
- 前脑动脉 (ACA) A1段未破裂的动脉瘤带来了治疗挑战.
- 内血管栓塞是一种常见的治疗方法,但精确的微导管导航至关重要.
研究的目的:
- 以计算流体动力学 (CFD) 模拟为指导的微导管成型的有效性进行评估.
- 评估该技术对后壁ACA A1段动脉瘤栓塞的影响.
主要方法:
- 对于未破裂的ACA A1段动脉瘤进行内血管栓塞的患者的回顾性分析.
- 微导管成型是基于CFD模拟的母动脉血流模式进行的.
- 分析了临床,程序和随访数据.
主要成果:
- 包括8名患者;所有微导管都成功塑造和导航.
- 在87.5%的病例中,完全堵塞了动脉瘤.
- 血管造影随访显示出良好的结果,其中83.3%的患者获得了雷蒙第I级.
结论:
- 以CFD指导的微导管成型是一种安全有效的方法来治疗ACA A1段动脉瘤.
- 这种技术增强了微导管导航,稳定性和在栓塞期间的支持.
- 它为复杂动脉瘤治疗提供了一个有前途的方法.
相关概念视频
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Applications of Integration to Find Blood Flow
Blood flow through a cylindrical blood vessel can be mathematically described using the principles of laminar flow, a regime in which fluid moves smoothly in parallel layers. In this model, the velocity of the blood is not uniform across the cross-section of the vessel; rather, it varies with the radial distance from the center. The maximum velocity occurs along the central axis, decreasing progressively toward the vessel walls, where it reaches zero due to viscous drag.Approximating Blood...


