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预测线粒体准信号及其分裂部位

Fukasawa Yoshinori1, Kenichiro Imai2, Paul Horton3

  • 1Center for Bioscience Research and Education, Utsunomiya University, Japan.

Methods in enzymology
|October 25, 2024
PubMed
概括

本章回顾了用于预测蛋白质中的线粒体准信号 (MTSs) 的计算工具. 它涵盖了工具使用,数据集准备和用于MTS预测和分析的计算方法.

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Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...
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Mitochondrial Protein Sorting

Mitochondria are double-membrane organelles of the eukaryotes involved in cellular metabolism, signaling, ATP synthesis, and programmed cell death.  Each of these processes requires specific proteins and enzymes that must be correctly sorted to the right mitochondrial subcompartment for the proper functioning of the organelle.
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Porin Insertion in the Outer Mitochondrial Membrane

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Energy to Drive Translocation

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