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在全血中通过高速样本准备和LC-MS/MS分析确定HbA1c的早期发展

Indranil Mitra1, Andreas Leinenbach2, Andrea Geistanger2

  • 1Roche Diagnostics GmbH, Nonnenwald 2, 82377, Penzberg, Germany. indranil.mitra@roche.com.

Analytical and bioanalytical chemistry
|October 25, 2024
PubMed
概括

一种新的液体染色学-双重质谱法方法快速确定全血中的糖化血红蛋白 (HbA1c). 这种更快,更准确的测定适用于常规的临床环境,改进了传统的HbA1c测试方法.

关键词:
临床LCMS的情况这就是HbA1c.高通量的高通量.在 LCMS/MS 中使用.蛋白质量化量化的蛋白质.

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Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
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