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通过线粒体功能障碍,甲酸暴露诱导了小鼠胎儿心脏的发育毒性

Yafei Guo1,2, Bowen Li1,2, Yu Yan1,2

  • 1Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

Cardiovascular toxicology
|October 25, 2024
PubMed
概括

环境暴露于二二乙基甲酸盐 (DEHP) 会损害小鼠胎儿心脏的发育. 暴露于DEHP会破坏线粒体功能和基因表达,导致先天性心脏病 (CHD) 的风险.

关键词:
遗传性心脏病是一种先天性心脏病.在DEHP中,DEHP是DEHP.线粒体功能障碍 线粒体功能障碍氧化应激是一种氧化应激.

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