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Updated: Jun 9, 2025

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
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Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

Published on: February 16, 2015

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一个碳介导的纯氨酸合成是基质母细胞瘤中temozolomide耐药性的基础

Kimia Ghannad-Zadeh1,2, Alyona Ivanova1,2, Megan Wu1

  • 1The Arthur and Sonia Labatt Brain Tumor Research Center, Hospital for Sick Children, Toronto, ON, Canada.

Cell death & disease
|October 25, 2024
PubMed
概括

表观遗传修饰剂ID-1通过上调单碳 purin 合成来促进质母细胞瘤的生长和temozolomide 耐药性. 针对这种代谢途径为复发性质母细胞瘤提供了潜在的治疗策略.

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