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Updated: Jun 9, 2025

Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs
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Published on: May 18, 2022

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删除MAB21L2的上游突出了进化保存的非编码序列对眼睛发育的重要性

Fabiola Ceroni1,2, Munevver B Cicekdal3,4,5, Richard Holt1

  • 1Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK.

Nature communications
|October 25, 2024
PubMed
概括

在MAB21L2附近的遗传变异会导致眼,微眼和结肠瘤 (AMC). 在MAB21L2上游的删除中,非编码元素会影响眼睛的发育,为AMC提供新的诊断见解.

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