肉症和脂肪分布对阴茎癌的结果的影响
Valerie Hartmann1, Simon Udo Engelmann1, Christoph Pickl1
1Department of Urology, St. Josef Medical Center, University Medical Center Regensburg, Regensburg, Germany.
Scientific reports
|October 25, 2024
概括
肉,肌肉质量的损失,影响阴茎癌的存活率. 这项研究发现,在阴茎癌患者中,sarcopenia是整体和癌症特异性生存的重要危险因素.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 肌肉质量和功能与年龄相关的下降,是众所周知的各种癌症的不良预后指标.
- 有限的研究存在于sarcopenia和脂肪分布对阴茎癌的结果的影响.
研究的目的:
- 调查肉类的患病率和身体组成 (包括脂肪分布) 在预测阴茎癌患者的存活率方面的作用.
主要方法:
- 对38名阴茎癌患者进行了回顾性分析.
- 骨肌肉质量和脂肪分布被评估使用腹部CT扫描在第三腰椎.
- 测量的主要参数包括骨肌肉指数 (SMI),psoas肌肉指数 (PMI),内脏肥胖和内脏与皮下脂肪的比率.
主要成果:
- 在26%的患者中发现了萨科佩尼亚.
- 较低的SMI,晚年,淋巴结转移,远程转移和阴茎轴癌是整体生存的重要预测因素.
- 较高的PMI和远程转移与癌症特异性存活率有关.
- 脂肪分布参数与生存率之间没有发现显著的关联.
结论:
- 石症在阴茎癌患者中普遍存在,并且与较差的整体和癌症特异性存活率显著相关.
- 需要进一步的研究来澄清脂肪分布在阴茎癌预后中的作用.
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