相关实验视频

Updated: Jun 9, 2025

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions
06:01

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Published on: January 7, 2019

7.2K

开发一种高通量选系统,针对PRL和CNNM之间的蛋白质-蛋白质相互作用

Yosuke Funato1, Mai Mimura2, Kazuto Nunomura3

  • 1Laboratory of Biorecognition Chemistry, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan. funato.yosuke.3i@kyoto-u.ac.jp.

Scientific reports
|October 25, 2024
PubMed
概括

研究人员开发了一种新的查系统,以识别抑制瘤性肝脏再生酸酶 (PRL) 蛋白与环林M (CNNM) 蛋白相互作用的化合物,有助于开发新的抗癌药物.

关键词:
复合选 复合选 复合选 复合选 复合选环M (CNNM) 是一种(HTRF) 的时间.一致的时间解析光共振能量转移 (HTR-FRET)肝脏再生酸酶 (PRL) 的使用蛋白与蛋白的相互作用 (PPI)

更多相关视频

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells08:38

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells

Published on: March 3, 2015

13.3K
Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation00:07

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation

Published on: August 21, 2019

8.3K

相关概念视频

Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
12.5K