研究一种基于酸的新型绿色消毒剂配方的抗菌效果
Esther W Mwangi1,2, Moshe Shemesh1, Victor Rodov1
1Institute of Postharvest and Food Sciences, Agricultural Research Organization, The Volcani Institute, 68 HaMaccabim Road, P.O. Box 15159, Rishon LeZion 7505101, Israel.
Foods (Basel, Switzerland)
|October 26, 2024
概括
使用酸,过氧化和乳酸的新型绿色消毒剂有效杀死大多数细菌. 它在Listeria innocua中诱导了一个可行的但不可培养的状态,为食品安全提供了洞察力.
科学领域:
- 微生物学 微生物学
- 食品安全 食品安全
- 绿色化学 绿色化学
背景情况:
- 越来越需要有效和安全的抗菌剂.
- 绿色消毒剂为传统消毒剂提供可持续的替代品.
- 了解微生物对新型配方的反应对于安全至关重要.
研究的目的:
- 研究一种新型绿色消毒剂配方的作用机制.
- 评估配方对各种细菌物种的疗效.
- 探索该配方的潜力,以诱导一种可行的但不可培养的 (VBNC) 状态.
主要方法:
- 使用胆酸 (GA),过氧化 (H2O2) 和DL-乳酸 (LA) 的绿色消毒剂的配方.
- 测试消毒剂对格拉姆阴性和格拉姆阳性细菌的杀菌作用.
- 评估细菌种群减少,活性氧物种 (ROS) 生成,细胞内ATP水平和膜完整性.
主要成果:
- 双配方 (GA + H2O2) 显示出广泛的杀菌活性.
- 三重配方 (GA + H2O2 + LA) 协同抑制了无辜的李斯特菌.
- 暴露于三重配方的L. innocua表现出VBNC状态,保持ATP池和膜完整性.
结论:
- 这种新型的绿色消毒剂显示出强大的抗菌活性.
- 三重配方有效控制L. innocua,诱导VBNC状态而不增加ROS.
- 该系统为研究食品安全中的VBNC现象提供了一个平台.
关键词:
3,4,5-三基烯酸 是一种三基烯酸.埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.李斯特里亚无辜的这就是ROSOS ROS.抗微生物配方的抗微生物配方食品安全 食品安全过氧化是一种过氧化.乳酸乳酸是什么意思 乳酸是什么意思协同效应是一种协同效应.可行的但不可培养 (VBNC)更多相关视频
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