附部神经内分泌新生瘤儿童的特征和治疗方法:单中心研究
Stefano Mastrangelo1,2, Giorgio Attinà1, Guido Rindi2,3
1Pediatric Oncology Unit, Department of Woman and Child Health Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.
Cancers
|October 26, 2024
概括
儿童的尾神经内分泌瘤 (ANEN) 是罕见的,通常是良性的. 这项研究发现,患有ANEN的儿科患者在没有额外手术的情况下获得了很好的结果,这凸显了需要协商一致的指导方针的需要.
科学领域:
- 儿科瘤学 儿科瘤学
- 胃肠道病理 胃肠道病理
- 手术瘤学手术瘤学
背景情况:
- 尾神经内分泌瘤 (ANEN) 是一种罕见的瘤,在尾切除术后经常偶然发现.
- 关于儿童群体中ANENs的数据有限,导致缺乏治疗和随访共识.
研究的目的:
- 分析来自单一中心和现有文献的患者数据,以提高对儿科ANEN的理解.
- 评估儿童ANEN的特征,管理和结果.
主要方法:
- 在1998年至2023年期间,对17名儿科患者进行了回顾性分析,这些患者在尾切除术后被诊断为ANEN.
- 评估出现的症状,手术程序,瘤组织学,术后工作和长期随访.
主要成果:
- 78%的ANEN位于尾尖,大多数瘤小于1厘米.
- 所有的瘤都具有明显的切除边缘;没有检测到剩余的瘤或转移.
- 患者经历了优秀的结果,没有复发,即使没有进一步的手术,超过6年的中位数随访.
结论:
- 儿科ANEN表现出与良性和良好预后一致的特征.
- 目前的管理和后续策略似乎有效,在大多数情况下不需要额外的手术.
- 由于儿科ANENs的罕见性,为其管理制定共识指南至关重要.
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