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相关概念视频

Development of the Heart01:27

Development of the Heart

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The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
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Fetal Circulation01:14

Fetal Circulation

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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Anatomy of the Heart01:27

Anatomy of the Heart

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The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
107.3K
Location and Orientation of the Heart01:13

Location and Orientation of the Heart

2.4K
The human heart, despite its modest size and weight, is an organ of remarkable strength and endurance. Roughly the size of a fist, the heart weighs between 250 and 350 grams and is nestled within the mediastinum, the medial cavity of the thorax. It extends obliquely for about 12 to 14 cm, resting on the superior surface of the diaphragm. The heart is positioned anterior to the vertebral column and posterior to the sternum, with two-thirds of its mass lying to the left of the midsternal line.
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Overview of the Heart01:07

Overview of the Heart

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The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's...
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Development of Blood Vessels01:07

Development of Blood Vessels

530
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
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En Face Endocardial Cushion Preparation for Planar Morphogenesis Analysis in Mouse Embryos
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胎盘-心脏轴:一个进化观点.

Jadyn Matthews1, Brammy Rajakumar1, Chrystalle Katte Carreon2,3

  • 1Division of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.

International journal of molecular sciences
|October 26, 2024
PubMed
概括

胎盘对于胎儿发育至关重要,它调解营养和氧气的传输. 胎盘发育和功能影响胎儿健康,包括先天性心脏病风险,使其成为进化医学的关键.

关键词:
遗传性心脏病是一种先天性心脏病.进化生物学是进化的生物学.胎盘 胎盘 胎盘 胎盘

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科学领域:

  • 发展生物学 发展生物学
  • 进化医学是一种进化医学.
  • 生殖生物学 生殖生物学

背景情况:

  • 胎盘对于胎儿发育至关重要,它介于母亲和胎儿之间的营养和氧气交换.
  • 胎盘发育与胎儿心血管系统有关,异常可能导致先天性心脏病.
  • 以胎盘功能障碍为特征的孕产妇前症等孕产妇疾病与先天性心脏病发病率增加有关.

研究的目的:

  • 审查胎盘的进化和发育方面.
  • 探索胎盘作为母亲环境和胎儿健康之间的调解者的作用.
  • 突出胎盘发育和功能对婴儿健康结果的影响.

主要方法:

  • 关于胎盘发育和功能的文献综述.
  • 分析胎盘异常与先天性心脏病之间的关系.
  • 探索胎盘在进化医学中的作用.

主要成果:

  • 胎盘对于胎儿生长至关重要,促进营养和氧气的转移.
  • 胎盘发育与胎儿心血管发育相似,其异常与先天性心脏病有关.
  • 胎盘功能障碍,如在孕前所见,增加了婴儿先天性心脏病的风险.

结论:

  • 胎盘是一个关键的器官,将母亲的环境与胎儿的健康联系起来.
  • 了解胎盘进化和发育对于解决婴儿健康问题至关重要,包括先天性心脏病.
  • 胎盘是进化医学的一个关键焦点,用于理解人类生物学和疾病.