住院儿科患者中COVID-19的严重程度概况
Vânia Chagas da Costa1,2, Ulisses Ramos Montarroyos1, Katiuscia Araújo de Miranda Lopes2
1Postgraduate Program in Health Sciences, Universidade de Pernambuco, Recife 50100-010, Pernambuco, Brazil.
住院患有COVID-19的儿童面临严重疾病的风险,特别是那些患有不受控制的喘,肥胖,咳或不到一年的儿童. 改善喘和营养管理对于这些儿科患者至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- COVID-19显著影响儿科患者群体,需要了解疾病严重性因素.
- 患有COVID-19的住院儿童需要详细的临床表征来指导管理.
研究的目的:
- 在住院儿童中确定与严重COVID-19结局相关的临床特征.
- 分析儿童COVID-19病例中导致严重疾病的风险因素.
主要方法:
- 一项流行病学队列研究涉及191名0-14岁儿童,他们在2020年3月至2021年6月期间因COVID-19住院治疗.
- 从医院流行病学中心和医疗记录中收集的数据,将严重程度分为严重 (危急/严重) 或不严重 (无症状/轻度/中度).
- 多变量分析用于确定临床概况和疾病严重程度之间的关联.
主要成果:
- 73.3%的住院儿童患有严重的COVID-19.
- 在46.6%的病例中观察到缺氧 (氧和率<95%).
- 严重COVID-19的危险因素包括不受控制的喘 (RR=13.2),超重/肥胖 (RR=3.21),咳 (RR=2.72),年龄在一年以下 (RR=3.23).
结论:
- 患有非控制性喘,超重/肥胖,咳或年龄在一年以下的儿童患重症COVID-19的风险更高.
- 强调需要加强医疗保健,特别是在管理喘和营养方面,对于脆弱的儿科COVID-19患者.
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