多可萨赫萨酸与极度早产婴儿的睡眠质量
Giovanna Rando Barion1, Pietra Giovanna Marghetti2, Patricia Zanotelli Cagliari1,3,4
1Postgraduate Program in Health and Environment, University of Joinville Region, Rua Paulo Malschitzki, Joinville 89219-710, SC, Brazil.
International journal of environmental research and public health
|October 26, 2024
概括
补充多可萨赫萨酸 (DHA) 并没有改善早产婴儿的睡眠质量. 在这个巴西队列研究中,出生体重百分位也与睡眠质量无关.
科学领域:
- 新生儿营养新生儿营养
- 儿科睡眠科学 儿科睡眠科学
- 欧米茄-3 脂肪酸 欧米茄-3 脂肪酸
背景情况:
- 关于多可萨赫萨酸 (DHA) 和睡眠时间的结果存在矛盾.
- 过早出生的婴儿往往会经历睡眠障碍,影响发育.
- 研究像DHA这样的营养干预措施对于改善婴儿健康结果至关重要.
研究的目的:
- 为了确定口服多可沙赫萨酸 (DHA) 对巴西极度早产婴儿睡眠质量的影响.
- 探索出生体重状况,DHA补充剂和婴儿睡眠质量之间的联系.
主要方法:
- 一项涉及59名巴西极度早产婴儿的队列研究 (Joinville Docosahexaenoic Acid Study - JoiDHA).
- 使用简要婴儿睡眠问卷评估睡眠质量,由父母/监护人回答.
- 婴儿被分为补充DHA的 (n=37) 和不补充 (n=22) 组.
主要成果:
- 睡眠质量差在出生体重低于第50百分位 (68.2%,p=0.045) 的婴儿中更为普遍.
- 普森回归分析表明,出生体重状态和睡眠质量之间没有显著的关联.
- 在这个队列中,多可萨赫萨酸 (DHA) 补充与改善睡眠质量无关.
结论:
- 12-24个月龄的睡眠质量与非常和极端早产婴儿的DHA补充没有显著的关联.
- 需要进一步研究增加DHA摄入量,以充分了解其对睡眠质量的影响.
- 营养策略需要进一步研究,以优化脆弱婴儿群体的睡眠.
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