人类DNA聚合酶的正规和非正规作用 η

Salma Bedaiwi1, Anam Usmani1, Michael P Carty1

  • 1DNA Damage Response Laboratory, Centre for Chromosome Biology, School of Biological and Chemical Sciences, University of Galway, Galway H91W2TY, Ireland.

Genes
|October 26, 2024
PubMed
概括

包括转化合成 (TLS) 在内的DNA损伤耐受性通路对于基因组稳定至关重要. DNA聚合酶Pol η在TLS中发挥着关键作用,防止DNA断裂并促进化学抵抗.

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