在老年患者中使用STOPP/START版本3并与版本2进行比较时,发现了潜在的不适当处方:一个横截面研究
Mikołaj Szoszkiewicz1, Ewa Deskur-Śmielecka1, Arkadiusz Styszyński1
1Geriatric Unit, Department of Palliative Medicine, Poznan University of Medical Sciences, 61-245 Poznan, Poland.
Journal of clinical medicine
|October 26, 2024
概括
与以前的版本相比,更新的STOPP/START版本3标准有效地识别了与多种药物治疗的老年患者的潜在不适当处方 (PIP). 这种增强的工具有助于提高老年人药物安全性.
科学领域:
- 老年医学 老年医学
- 临床药房 临床药房
- 药物监督 药物监督 药物监督
背景情况:
- 老年人的多病症和多药性导致药物管理面临重大挑战.
- 包括药物和遗漏在内的潜在不适当处方 (PIP) 需要强大的识别工具.
- 现有的工具,如酒清单,FORTA和STOPP/START标准,旨在减轻PIP.
研究的目的:
- 评估老年患者中通过STOPP/START版本3识别的PIP的患病率和数量.
- 为了比较STOPP/START版本3的检测率与之前的版本.
- 评估更新的STOPP/START标准在识别老年人药物相关问题的有效性.
主要方法:
- 一项涉及100名多药老年患者的回顾性,横截面研究.
- 收集的数据包括来自波兰两个日托中心的人口统计和医疗信息.
- 使用STOPP/START版本3来识别PIP,使用版本2作为比较参考.
主要成果:
- 在73%的患者中,STOPP版本3确定了至少一种潜在不合适的药物 (PIM),从版本2的56%显著增加.
- START版本3显示了潜在的处方遗漏 (PPO) 的更高的流行率 (74%与57%对比),以及每人更多的PPO.
- 常见的PIM涉及NSAID (包括阿司匹林),而频繁的PPO包括缺少透性松剂,MRA和SGLT-2抑制剂在心力衰竭中.
结论:
- STOPP/START版本3在多种药物治疗的老年患者中检测PIP的高效性.
- 更新的标准显示,与版本2相比,PIM和PPO的检测率显著更高.
- 这种增强的工具对于改善老年人群中药物安全性和适当性至关重要.
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