相关实验视频
Updated: Jul 21, 2026

10:32
Mechanical Testing of Mouse Carotid Arteries: from Newborn to Adult
Published on: February 23, 2012
12.7K
在2至40岁的健康个体中,对常常动脉进行机械绘图
Roch Listz Maurice1,2, Nagib Dahdah3
1Centre de Recherche Charles-Le Moyne (CRCLM), Centre Intégré de Santé et des Services Sociaux de la Montérégie-Centre (CISSSMC), Longueuil, QC J4K 0A8, Canada.
Journal of clinical medicine
|October 26, 2024
概括
这项研究在2-40岁的健康个体中绘制了常见动脉 (CCA) 的机械特性. 研究结果显示,CCA硬度的年龄相关变化有助于早期预测和预防中风和心血管疾病.
科学领域:
- 心血管医学 心血管医学
- 生物医学工程 生物医学工程
- 预防性心脏病学 预防性心脏病学
背景情况:
- 卒中是导致死亡和残疾的主要原因,全球每年有超过1220万例新发病例.
- 缺血性中风,通常与大动脉动脉样硬化有关,占中风病例和死亡率的很大一部分.
- 早期发现风险因素对于预防中风和相关心血管疾病至关重要.
研究的目的:
- 为了研究健康的常见动脉 (CCA) 的年龄依赖的机械特性.
- 通过非侵入性动脉硬性评估来预测中风风险的基线.
- 支持用于预防心血管疾病的早期干预策略.
主要方法:
- 在95名健康女性 (2.23-39.46岁) 和107名健康男性 (2.85-40岁) 中评估了CCA度.
- 使用传统的医疗超声波来记录B模式的CCA电影循环.
- 估计动脉壁弹性模块使用基于非侵入性成像的生物标志物算法 (ImBioMark).
主要成果:
- 已建立的CCA弹性模块在女性 (41 ± 2 kPa至54 ± 17 kPa,R2 = 0.88) 和男性 (38 ± 5 kPa至63 ± 22 kPa,R2 = 0.83) 中的线性回归概况.
- 在CCA中表现出与年龄相关的明显机械进化模式,适用于两性.
- 提供了定量数据,以与病理状况比较,如川崎病和早产.
结论:
- 介绍了对年轻成年人中CCA的年龄相关机械变化的基本见解.
- 通过评估CCA的机械性质,突出了通过评估CCA机械性质来预测中风和心血管疾病的早期风险的潜力.
- 支持转向心血管健康的预测和预防医学.
相关概念视频
Assessing Blood pressure using a doppler ultrasound
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
Arteries of the Upper Limbs
The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
Arteries of Lower Limbs
The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Imaging Studies for Cardiovascular System III: X-Ray
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

