衰老和膝关节关节炎对下肢对齐和CPAK分类的影响:日本队列中的性别差异
Kento Harada1, Yu Mori1, Masayuki Kamimura1
1Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Journal of clinical medicine
|October 26, 2024
概括
这项研究揭示,老化和膝关节骨关节炎 (OA) 对日本男性和女性的下肢冠状元对齐有不同的影响. 骨关节炎的进展将对齐转移到,改变了膝盖冠状平面对齐 (CPAK) 的分类,特别是在女性身上.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 生物机械工程 生物机械工程
背景情况:
- 膝关节骨关节炎 (OA) 是一种退行性关节疾病,影响下肢对齐.
- 冠状元平面对齐对于理解生物力学和OA进展至关重要.
- 膝盖冠状平面对齐 (CPAK) 分类系统对膝盖对齐进行了分类.
研究的目的:
- 调查年龄和膝盖OA对日本男性和女性下肢冠状元对齐的影响.
- 分析机械角度和关节线斜率 (JLO) 随着老化和OA的变化.
- 确定这些因素如何影响研究人口中的CPAK分类.
主要方法:
- 对150名男性和150名女性进行横截面分析,按年龄和OA严重程度分层.
- 从数字长腿X射线图中测量机械侧侧偏远大腿角 (mLDFA) 和机械中侧近接角 (mMPTA).
- 计算算术关节-膝盖-脚角 (aHKA) 和JLO,然后进行CPAK分类.
主要成果:
- 随着男性的衰老和男性的老龄化,在两种性别中都观察到增加的肌对齐 (较小的aHKA) 与OA进展.
- 与男性不同的是,女性在老化和OA时表现出向mMPTA的varus转移,与男性不同.
- 从CPAKII型转变为I型,并随着OA的进展,女性受老龄化的影响.
结论:
- 衰老影响膝盖冠状线对齐和CPAK分类在性别之间不同.
- 骨关节炎的进展始终导致更多的向对齐 (较小的aHKA),JLO保持稳定.
- 与其他种族相比,日本人群在OA受影响的个体中显示出明显的CPAK变异,这表明潜在的种族差异.
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