对六种乳杆菌菌株的生长和新陈代谢特征的比较研究,通过化酸
Longrui Wang1,2,3, Jiasheng Ju3,4, Huichun Xie1,2,3
1Key Laboratory of Medicinal Plant and Animal Resources of the Qinghai-Tibetan Plateau in Qinghai Province, Xining 810008, China.
Microorganisms
|October 26, 2024
概括
补充对某些乳酸菌菌株有好处,改变了它们的生长和代谢概况. 这些微生物将无机转化为有机形式,影响营养同化和应激反应.
科学领域:
- 微生物学与营养科学 微生物学与营养科学
- 代谢学和生物化学
背景情况:
- (Se) 是对人类和动物健康至关重要的微量营养素.
- 微生物具有将无机转化为有机形式的能力.
- 乳酸菌是重要的益生菌,在生物转化中具有潜在的作用.
研究的目的:
- 为了研究胺对六种乳酸菌菌株的生长和代谢概况的影响.
- 为了确定特定的代谢物和代谢途径受影响的暴露在乳酸菌.
- 了解乳酸菌菌株对的不同反应.
主要方法:
- 六种乳酸菌株被暴露在50μg/mL的烯酸盐中.
- 细胞数量和体重被测量以评估生长.
- 气色谱并联飞行时间质谱 (GC-TOF-MS) 用于代谢分析.
- 分析了271种已识别的代谢物和相关的代谢途径.
主要成果:
- 显著增加了四种乳酸菌菌株 (Lacticaseibacillus rhamnosus PS5,Lbs. 拉姆诺苏斯RT-B,Limosilactobacillus reuteri 3630和Lmb. 这两种类型的植物都被发现. 雷特里 (Reuteri 1663) 在1663年出版.
- 代谢分析显示有机酸,氧化合物,脂质和类化合物的显著变化.
- 提高血清素,青酸,三糖,棕酸,甲基三胺和 melibiose 的调节;降低葡萄糖酸,糖,甲酸和甲酸的调节.
- 参与ABC载体,氨基酸代谢 (甘氨酸,氨酸,三氨酸) 和降解途径的代谢途径发生了显著的改变.
结论:
- 乳酸菌在接触时表现出改变的运输,吸收,同化和应激反应机制,这是代谢变化所证明的.
- 针对的特定代谢变化在不同的乳酸菌菌株之间因其独特的特性而有所不同.
- 这些发现凸显了特定乳酸菌株在生物转化和生物强化方面的潜力.
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