益生菌-Ichnos:具有体内益生菌特性的微生物数据库
Margaritis Tsifintaris1, Despoina Eugenia Kiousi1, Panagiotis Repanas1
1Department of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Microorganisms
|October 26, 2024
概括
益生菌-ichnos是一个新的数据库,详细介绍了具有体外益生菌特性的微生物菌株. 它组织了关于菌株特征和全基因组序列的数据,以帮助对有益微生物的研究.
科学领域:
- 微生物学 微生物学
- 生物信息学是一种生物信息学.
- 食品科学 食品科学 食品科学
背景情况:
- 益生菌是活生生的微生物,通过调节宿主平衡来赋予健康益处.
- 乳酸细菌 (LAB),酵母和Bacillus物种是常见的益生菌的例子.
- 现有的文献缺乏一个集中,精心策划的资源,用于体外益生菌菌株数据.
研究的目的:
- 介绍Probio-ichnos,这是第一个手工策划的微生物菌株数据库,具有体外益生菌特征.
- 综合并呈现来自不同来源的关于菌株属性的全面信息.
- 通过对益生菌菌株进行有针对性的验证和比较分析来促进研究.
主要方法:
- 在PubMed的系统文献搜索中,使用关键字"益生菌".
- 手动过了27,715项研究,以确定2207个具有体外实验数据的相关出版物.
- 提取有关菌株特定益生菌属性的数据 (例如,抗酸/胆,抗菌活性) 和全基因组序列可用性的数据.
主要成果:
- 益生菌-ichnos数据库包含12993条关于体外益生菌特征的条目.
- 数据涵盖了11202个不同的菌株,涉及470个物种和143个属.
- 信息是使用益生菌属性的二进制分类来呈现的,包括全基因组序列可用性.
结论:
- 益生菌-ichnos为研究益生菌的研究人员提供了一个有价值的,基于文献的资源.
- 该数据库简化了对体外益生菌数据的访问,支持菌株选择和验证.
- 它旨在加快有益微生物菌株的发现和应用.
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