地中海饮食对功能性胃肠道疾病患者肠道微生物群,症状和标志物的影响
Elena Garicano Vilar1, Sara López Oliva1, Bruno F Penadés1
1Research Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Microorganisms
|October 26, 2024
概括
地中海饮食 (MD) 改变了胃肠道 (GI) 疾病患者的肠道真菌,减少了一些真菌,增加了其他真菌. 这种饮食干预也改善了胃肠道症状和肠道细菌的关联.
科学领域:
- 胃肠道学和微生物学
- 饮食干预和肠道健康
背景情况:
- 地中海饮食 (MD) 对肠道细菌有积极的影响,但其对肠道真菌和胃肠道 (GI) 疾病的影响尚不清楚.
- 研究MD对真菌肠道微生物群和胃肠道症状的影响对于了解其治疗潜力至关重要.
研究的目的:
- 评估地中海饮食对肠道微生物多样性和结构对肠道疾病患者的影响.
- 为了评估6周的MD干预后肠道症状和生物标志物的变化.
主要方法:
- 在46名患有胃肠道疾病的患者中,使用地中海饮食 (MD) 进行了为期6周的饮食干预.
- 对肠道真菌和细菌微生物群的组成和多样性的分析.
- 评估胃肠道症状和相关生物标志物.
主要成果:
- 医学药物干预显著改变了真菌肠道微生物群的组成,减少了Sordariomycetes,Leotiomycetes,Orbiliomycetes, Chytridiomycota和Mucoromycota,同时增加了Saccharomycetes.
- 细菌微生物群的组成保持不变.
- 患者经历了各种胃肠道疾病的减少.
- 他们发现了便的一致性,肠道透性和细菌属Alistipes和Roseburia之间的关联.
结论:
- 地中海饮食可以调节患有肠道疾病的患者的真菌肠道微生物群.
- MD干预显示出改善胃肠道症状和相关生物标志物的潜力.
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