黑种子油对口服微观宇宙生物膜的抗菌作用
1Department of Health Science, Gachon University Graduate School of Public Health, Incheon 21936, Republic of Korea.
Microorganisms
|October 26, 2024
概括
黑种子油 (BCSO) 在治疗口服生物膜方面表现出与素酸盐 (CHX) 相当的抗菌作用. BCSO有效地减少生物膜中的活细菌,为口腔护理提供了潜在的天然替代品.
科学领域:
- 口腔微生物学 口腔微生物学
- 自然产品化学 自然产品化学
背景情况:
- 对于用于口服生物膜管理的天然提取物越来越感兴趣.
- 黑子种子油 (BCSO) 显示出对抗*Streptococcus mutans*的承诺.
- 需要多种生物膜模型来评估抗菌疗效.
研究的目的:
- 为了比较BCSO和赫西丁葡萄糖酸盐 (CHX) 对口服微观生物膜的抗菌作用.
- 评估BCSO作为口腔卫生中CHX的潜在替代品.
主要方法:
- 培养的人类唾液注射口服生物膜2天.
- 每天用0.5%的BCSO或0.12%的CHX处理6天的生物膜.
- 评估生物膜红色光强度 (RatioR/G),生物质 (EPS,活细菌) 和酸性细菌CFU.
主要成果:
- BCSO治疗显示RatioR/G (1.26 ± 0.03) 和EPS水平与CHX.相比.
- 在BCSO组与CHX组相比,活细菌的数量明显较低 (0.55倍).
- 在BCSO和CHX组之间,酸性细菌CFU没有显著差异.
结论:
- 在口服生物膜上,BCSO表现出与CHX相似的抗菌作用.
- BCSO有效地减少了口腔生物膜中的活细菌.
- BCSO具有作为口腔护理的有效天然替代品的潜力.
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