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Updated: Jun 9, 2025

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SARS-CoV-2核体蛋白对抗GADD34-通过非典型焦点介导的先天性免疫路径

Jie Liu1,2, Guanwen Guan2, Chunxiu Wu2

  • 1Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.

Molecules (Basel, Switzerland)
|October 26, 2024
PubMed
概括

在SARS-CoV-2核体蛋白形成非典型的压力颗粒,阻断GADD34表达和IRF3激活. 这会损害宿主免疫力,有助于病毒复制和致病的产生.

关键词:
在GADD34中,GADD34是什么意思?这就是SARS-CoV-2病毒.这是先天免疫力.核体蛋白质是核体蛋白质的一种.压力颗粒是压力颗粒.

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