与多药和免疫接种有关的COVID-19 (2020-2024)
Anna Puigdellívol-Sánchez1,2, Marta Juanes-González1, Ana Calderón-Valdiviezo1
1Medicina de Família, CAP Anton de Borja Centre Universitari, c/ Marconi-Cantonada Edison s/n, Consorci Sanitari de Terrassa, 08191 Rubí, Spain.
Viruses
|October 26, 2024
概括
70岁以上的老年人患有多种慢性疾病 (≥5nT) 并且以前没有COVID-19感染,风险较高. 优先考虑预防策略,如更新疫苗接种和早期治疗,对于减少住院治疗至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 老年病的医生 老年病的医生
背景情况:
- 观察性研究表明,多药与更糟糕的COVID-19结果有关.
- 慢性抗胰岛素使用可能会降低COVID-19入院率和死亡率.
- 了解各种变异的住院患者的个人资料是未来研究的关键.
研究的目的:
- 分析住院COVID-19患者的个人资料.
- 确定针对性预防策略的特定患者群体.
- 为了告知未来对COVID-19管理的潜在试验.
主要方法:
- 在特拉萨医院对1457名COVID-19住院患者的回顾性分析.
- 从2020年3月到2024年8月从167,386.6人的人口中收集的数据.
- 分析包括年龄,性别,慢性治疗次数 (nT) 和免疫状态.
主要成果:
- 在291名住院患者中 (2023年5月以后),70.2%的患者年龄超过70岁,39%的患者接受了超过8次慢性治疗.
- 疫苗接种情况有所不同,12%未接种疫苗,59%接种了≥4种疫苗.
- 大多数没有接种疫苗的住院病例 (>60年) 可能是德尔塔或欧米克朗变种造成的.
结论:
- 70岁以上的患者,经过5次以上的慢性治疗并且没有先前的感染,风险较高.
- 应优先考虑针对这一群体的预防策略.
- 建议更新疫苗接种和早期治疗,以减少住院治疗.
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