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Updated: Jun 26, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
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的微改性HIV-1感染:当前模型的发展,实用性和局限性

Manish Sharma1, Mukta Nag1, Gregory Q Del Prete1

  • 1AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

Viruses
|October 26, 2024
PubMed
概括

在中开发最小修饰的HIV-1 (mmHIV-1) 为HIV-1研究提供了比SIV更好的模型. 一种新的mmHIV-1克隆,stHIV-A19,在猪尾中显示出有前途的结果,导致与CD8α+细胞枯竭的艾滋病类似的结果.

关键词:
艾滋病 艾滋病 艾滋病是什么?艾滋病病毒-1 艾滋病病毒-1这就是SIV SIV.动物模型动物模型马可克 (Macaque) 是一个巨.非人类灵长类的灵长类.

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