在患有密码性中风的患者中,通过导管PFO关闭后中风复发
Bea Goessinger1, Stefan Greisenegger2, Stefan Kastl1
1Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
概括
通过管关闭 patent foramen ovale (PFO) 提供了对密码性中风的安全有效的长期二次预防. 像RoPE和PASCAL这样的预测得分有助于选择可能受益于PFO关闭的患者.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 干预心脏病学 干预心脏病学
背景情况:
- 专利卵孔 (PFO) 关闭建议用于加密性中风的二次预防.
- 对于PFO关闭的长期结果数据有限.
- 透导管PFO关闭的目的是减少神经系统的复发.
研究的目的:
- 评估跨导管PFO关闭的长期安全性和有效性.
- 为了确定PFO关闭后神经复发的预测因素.
主要方法:
- 分析了在2010-2015年期间接受PFO关闭的330名患者的队列.
- 短期和长期随访评估过渡性缺血性攻击 (TIA),中风或与中风相关的死亡.
- 预测得分 (RoPE,PASCAL) 和患者病史被评估,以预测复发.
主要成果:
- 与手术相关的并发症发生在2.4%的患者中.
- 在平均10年的随访期间,联合终点发生在3.6% (复发率:0.38/100患者年).
- 罗佩分数,帕斯卡分类和先前的神经事件独立预测复发.
结论:
- 超导管PFO关闭表明长期神经事件的复发率较低,特别是在密码性中风中.
- 罗佩分数,帕斯卡分数和先前的事件是复发的关键预测因素.
- 这项研究支持PFO关闭对二次中风预防的安全性和有效性,强调患者选择.
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