Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

18.8K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.8K
Genomics02:02

Genomics

36.1K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.1K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

2.4K
2.4K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

46.7K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
46.7K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

12.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Vertebrate Genomes Project Phase I: A global reference genome resource.

bioRxiv : the preprint server for biology·2026
Same author

Servo-Actuated 3D-Printed Disposable Microvalves for Automated, Scalable Organoid Culture in Standard Incubators.

bioRxiv : the preprint server for biology·2026
Same author

Cloud-connected pluripotent stem cell platform enhances scientific identity in underrepresented students.

Stem cell reports·2026
Same author

Intrinsic coordination of dynamic molecular signatures shape the human prefrontal cortex.

bioRxiv : the preprint server for biology·2026
Same author

SpikeLab: Agentic tools for spike data analysis.

bioRxiv : the preprint server for biology·2026
Same author

Microfluidic Control of Dorsal-Ventral Patterning Within a Single Forebrain Organoid.

bioRxiv : the preprint server for biology·2026

相关实验视频

Updated: Jun 9, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.3K

该UCSC基因组浏览器数据库:2025年更新更新

Gerardo Perez1, Galt P Barber1, Anna Benet-Pages2,3

  • 1Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

Nucleic acids research
|October 26, 2024
PubMed
概括
此摘要是机器生成的。

该UCSC基因组浏览器提供增强的基因组数据可视化与新的注释轨道,改进的导航,并扩展数据访问. 这种基本的生物信息学工具现在为世界各地的研究人员提供了一个用户友好的界面.

更多相关视频

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.1K
Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq
10:23

Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

Published on: February 26, 2015

12.4K

相关实验视频

Last Updated: Jun 9, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.3K
A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.1K
Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq
10:23

Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

Published on: February 26, 2015

12.4K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学

背景情况:

  • 该UCSC基因组浏览器是一个重要的基于Web的平台,用于基因组数据的可视化和分析.
  • 它拥有超过4000个汇编和来自内部和社区来源的各种注释数据.
  • 它成立于2001年,仍然是科学界的基石资源.

研究的目的:

  • 详细介绍UCSC基因组浏览器的最新更新和改进.
  • 突出新功能,增强数据可访问性和用户体验.
  • 展示平台作为领先的基因组学资源的持续发展.

主要方法:

  • 整合了新的注释轨道,包括GRCh38/hg38.8上的gnomAD 4.1
  • 扩展基因组档案 (GenArk) 系统用于组装管理.
  • 接口增强:弹出对话框,改进的轨道导航和分组功能.

主要成果:

  • 增加了超过25条新的注释轨道和3个公共枢纽.
  • 用户界面的显著改进,用于数据探索和导航.
  • 增强了GenePred轨道和轨道枢纽管理的功能.

结论:

  • 该UCSC基因组浏览器继续扩大其功能,提供新的数据和功能.
  • 最近的更新提高了基因组研究的可用性和数据可访问性.
  • 该平台仍然是全球基因组学和生物信息学社区的关键资源.