在桃体切除术后出血病例中,动因菌状况和炎症生物标志物
Burak Hazır1, Zeliha Berfu Kastal1, Eray Uzunoğlu2
1Department of Otorhinolaryngology/Head and Neck Surgery, Ankara City Hospital, Ankara, Turkey.
Acta oto-laryngologica
|October 26, 2024
概括
在桃体中Actinomyces的存在与桃体切除术后出血无关. 然而,像NLR和SIRI这样的炎症标志物增加与Actinomyces有关,这表明系统性炎症反应.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- Actinomyces感染可能导致各种并发症.
- 了解Actinomyces在桃体切除术结果中的作用至关重要.
研究的目的:
- 为了研究在口腔桃体中Actinomyces的频率.
- 为了确定Actinomyces和桃体切除术后出血 (PTH) 之间的关联.
- 分析与Actinomyces和PTH相关的血清炎症生物标志物水平.
主要方法:
- 一项对1137名接受桃体切除术的患者的回顾性研究.
- 针对Actinomyces存在的组织病理学检查.
- 从全血计数计算中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR),系统性免疫炎症指数 (SII) 和系统性炎症反应指数 (SIRI).
主要成果:
- 在8.18%的患者中检测到actinomyces;5.72%的患者经历出血并发症.
- 在Actinomyces和PTH率之间没有发现显著的关联 (p=0.433).
- 年龄,NLR和SIRI与Actinomyces状态存在关联 (分别p<0.001,p=0.017,p=0.038).
结论:
- 在Actinomyces患者中观察到较高的NLR和SIRI值,表明潜在的全身表现.
- 血清炎症生物标志物和Actinomyces的存在与桃体切除术后出血没有直接联系.
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