相关实验视频

Updated: Jun 9, 2025

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

在膀癌幸存者中,随后出现一次性癌症的风险较大

Yadong Guo^1,2, Yuke Zhang^1,2, Shiyu Mao^1,2

¹Department of Urology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, 200072, People's Republic of China.

Clinical and experimental medicine

|October 26, 2024

概括

膀癌幸存者面临特定后续原发性癌症 (SPC) 的风险增加. 这项研究强调了某些癌症的高风险,为幸存者提供了关键的临床后续策略.

科学领域:

在瘤学瘤学.
癌症流行病学癌症流行病学
公共卫生公共卫生

背景情况:

膀癌 (BCa) 幸存者有患二次恶性瘤的风险.
了解后续原发性癌症 (SPC) 风险对于幸存者护理至关重要.

研究的目的:

在BCa幸存者中调查15个SPC的发病率和死亡风险.
根据诊断以来的性别和时间,在BCa幸存者中识别特定的SPC风险较高.

主要方法:

使用了监测,流行病学和最终结果 (SEER) 数据库.
分析了229,554名BCa幸存者的数据,以计算发病率,死亡率,绝对超额风险 (AER),标准化发病率 (SIR) 和标准化死亡率 (SMR).

主要成果:

幸存者BCa显示显著增加了几种SPCs的发展和死亡的风险.
结直肠,乳腺,肝脏,胰腺,尿管,脏,盆,肺和宫癌的风险增加,因性别和诊断后的时间而异.
较年轻的幸存者和在诊断后一年内的幸存者具有不同的SPC风险概况.

结论:

患有BCa的幸存者患上和死于特定SPC的风险显著增加.
这些发现强调了为BCa幸存者制定量身定制的监测协议的必要性,以早期检测SPC.
这项研究为优化膀癌幸存者的长期临床管理提供了关键的基础.

关键词:

膀癌幸存者膀癌幸存者风险风险风险风险风险塞尔·塞尔 (Seer) 是一个看得见的人.随后的原发性癌症.

更多相关视频

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

相关概念视频

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...