加拿大成年人体构成参考数据,椎骨分数和使用DXA的高级部分析
Lauren A Burt1, Liam T Pond2, Annabel R Bugbird2
1McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada; Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
概括
这项研究提供了关键的年龄和性别特定的参考数据,用于内脏脂肪组织 (VAT) 和先进的部分析 (AHA) 使用双X射线吸收计 (DXA). 这些发现为评估成年人一生的身体组成和骨健康提供了有价值的工具.
科学领域:
- 骨质疏松症和身体组成研究
- 老年学和成人健康研究研究.
背景情况:
- 对于成年人一生中从双X射线吸收计 (DXA) 获得的内脏脂肪组织 (VAT) 和高级部分析 (AHA) 参数,存在有限的参考数据.
- 准确评估身体组成和骨健康需要全面的,年龄和性别特定的规范性数据.
研究的目的:
- 开发年龄,部位和性别特定的参考数据,用于DXA衍生的身体组成,椎骨分数 (TBS) 和AHA参数.
- 为临床医生和研究人员建立加拿大参考数据,以评估成人身体组成和骨质.
主要方法:
- 一组908名20岁及以上的成年人 (561名女性,347名男性) 接受了部,腰椎,前臂和全身的DXA扫描.
- 分析了面积骨矿物质密度 (aBMD),身体成分 (瘦质量,脂肪质量,脂肪百分比),VAT质量,AHA参数和TBS.
- 位置,尺度和形状 (GAMLSS) 的通用添加模型被用来生成特定地点和性别的百分曲线和表格.
主要成果:
- 在成年人一生中成功生成了DXA衍生的VAT和AHA参数的综合参考数据.
- 特定于位置和性别的百分曲线和表格为身体组成,TBS和AHA提供了规范值.
- 开发的参考数据适用于加拿大人口.
结论:
- 这项研究成功地开发并呈现了DXA衍生的身体组成,VAT,TBS和AHA参数的年龄,地点和性别特定的参考数据.
- 这些加拿大参考数据是评估成人健康的宝贵临床和研究工具.
- 这些发现有助于更好地了解整个成年期的身体组成和骨健康变化.
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