儿童虐待,认知表现和中年和老年慢性病患者的认知衰退:一项前性研究
Ann Xiuli Chicoine1, Howard Chertkow2, Jean-Claude Tardif3
1Research Centre, Montreal Heart Institute, Montreal, Canada; Psychology Department, Université de Montréal, Montreal, Canada.
Journal of psychosomatic research
|October 26, 2024
概括
童年虐待与慢性疾病的老年人认知功能较差有关. 然而,在这项研究中,它没有预测在五年内进一步的认知衰退.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 心理学 心理学 心理学
背景情况:
- 童年虐待 (CM) 是认知缺陷和痴呆症的潜在风险因素.
- 以前的研究往往是横截面的,专注于特定类型的CM,忽视了个体差异.
- 在患有慢性疾病的个体中,CM对认知轨迹的影响需要进一步研究.
研究的目的:
- 评估CM是否预测5年内冠状动脉疾病 (CAD) 或其他非心血管 (非CVD) 慢性疾病的老年人认知表现较差和认知衰退较大.
- 为了确定性别和CAD状态是否影响CM和认知功能之间的关系.
主要方法:
- 1254名患有CAD或其他慢性疾病的男性和女性填写了儿童创伤问卷简单表格 (CTQ-SF).
- 在基线和5年随访后,使用蒙特利尔认知评估 (MoCA) 评估认知表现.
- 使用两变相关性,层次分析和适度分析,控制社会人口统计学和健康因素.
主要成果:
- 32%的参与者报告经历了CM. 认知缺陷在基线时存在32.7%,在随访时存在40.2%.
- 在基线,CM与较低的MoCA得分显著相关 (p=0.020),但与随时间推移的认知能力下降无关 (p=0.796).
- 虽然性别和CAD状态影响了MoCA分数,但它们并没有缓解CM和认知表现之间的关联.
结论:
- 童年虐待预测慢性疾病的老年人认知功能较差.
- 在这个队列中,CM没有预测在5年的随访期内进一步的认知衰退.
- 需要进一步的研究来阐明CM与认知健康联系的潜在机制.
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