在完整的左分支阻塞患者的亚临床左心室缩功能障碍中,顶摇摆和隔膜闪光的预测值与正常的左心室射出小部分患者的左心室缩功能障碍
Mengjia Chen1, Bo Pang1, Guangyuan Li1
1Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, Liaoning, China; Clinical Medical Research Center of Imaging in Liaoning Province, Shenyang, Liaoning, China.
International journal of cardiology
|October 26, 2024
概括
圆顶摇摆 (ApRock) 和隔膜闪光 (SF) 表明左心室功能减少在完整的左捆分支阻塞 (CLBBB) 患者. ApRock和SF的组合是亚临床左心室功能障碍的强有力的预测因素.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏电生理学 心脏电生理学
背景情况:
- 完整的左捆分支阻塞 (CLBBB) 与正常的喷射分数 (LVEF) 可以呈现亚临床左心室功能障碍.
- 具有保存LVEF的CLBBB患者的风险分层需要识别微妙的功能障碍.
研究的目的:
- 为了评估顶端摇摆 (ApRock) 和隔膜闪光 (SF) 对左心室 (LV) 功能在正常LVEF的CLBBB患者的影响.
- 评估ApRock和SF对该患者队列风险分层和临床决策的有用性.
主要方法:
- 75名正常LVEF的CLBBB患者和30名对照患者接受了心声回声扫描.
- 三名医生对ApRock和SF进行视觉评估.
- 量化LV全球纵向应变 (LVGLS) 和时间到峰值应变 (Ts-SD) 的标准偏差,使用二维斑点跟踪回声心脏学.
主要成果:
- 具有正常LVEF的CLBBB患者表现出LV功能和同步性受损 (LVGLS降低,Ts-SD增加).
- 存在ApRock或SF与较低的LVGLS有关.
- 联合ApRock和SF显著降低了LVGLS,增加了Ts-SD (P<0.001).
- ApRock和SF是LVGLS<-20%的独立预测指标,并且在组合时显示出最高的预测值.
结论:
- 具有正常LVEF的CLBBB患者表现出缩功能受损.
- ApRock和SF的组合是亚临床LV损伤的强有力的指标,超过了个别发现.
- 需要对正常LVEF的CLBBB患者进行密切监测,特别是那些患有ApRock和SF的患者.
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