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Updated: Jul 15, 2026

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
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Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons

Published on: October 8, 2014

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类化合物/盐 (尼古丁,尼古丁酸,咖啡因和阿雷科林化物) 之间的激发性差异的分子成像

Dawei Yan1, Xiaomin Liu1, Yihan Gao1

  • 1Shanghai New Tobacco Product Research Institute Co., LTD., NO. 3733 Xiupu Road, Shanghai 201315, China.

Journal of pharmacological and toxicological methods
|October 26, 2024
PubMed
概括

一种新的正电子发射断层扫描 (PET) 成像技术非侵入性地测量了老鼠的类激发性. 这项研究确定了尼古丁,尼古丁酸,咖啡因和阿雷科林酸的刺激性和效应和基于性别的差异.

关键词:
类化合物 类化合物兴奋能力 兴奋能力吸入式吸入方式在PET成像中使用PET成像.

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FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation08:31

FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation

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相关概念视频

Cholinergic Receptors: Nicotinic01:15

Cholinergic Receptors: Nicotinic

Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:22

Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
The direct-acting...