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树突细胞内在的PTPN22负面调节抗瘤免疫力,并影响抗PD-L1疗效

Santiago Acero-Bedoya1, Emily F Higgs2, Anna C Martinez1

  • 1Pathology, University of Chicago Biological Sciences Division, Chicago, Illinois, USA.

Journal for immunotherapy of cancer
|October 26, 2024
PubMed
概括

在树突细胞中去除PTPN22通过增强T细胞反应和瘤控制来增强抗瘤免疫力. 这表明PTPN22是癌症免疫治疗的潜在治疗标.

关键词:
树突性 树突性 树突性遗传学 遗传学 是一种遗传学.免疫治疗是一种免疫疗法.骨髓状细胞是什么? 骨髓状细胞是什么?固体瘤是一个固体瘤.

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