患有乳腺癌的抑郁患者的心率变化和失眠
Qianqian Zhang1, Sheng Yu2, Lingxue Tang2
1Second Affiliated Hospital of Anhui Medical University, Hefei, China.
BMJ supportive & palliative care
|October 26, 2024
概括
乳腺癌患者的抑郁症严重程度与较差的心率变化 (HRV) 和睡眠质量有关. 自主神经系统的动态反映了这些患者的抑郁水平.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 精神病学是一个精神病学.
背景情况:
- 自主神经系统的调节对整体健康至关重要.
- 抑郁症是乳腺癌 (BC) 患者常见的并发症.
- 在BC患者中,抑郁症严重程度与自主功能之间的关系需要进一步阐明.
研究的目的:
- 在BC患者中研究线性和非线性心率变化 (HRV) 参数的差异,这些患者的抑郁程度各不相同.
- 在BC患者中探索HRV参数,抑郁症严重程度和睡眠质量之间的关联.
主要方法:
- 115名BC患者根据自我评价抑郁度量 (SDS) 评分进行分类:非抑郁,轻度抑郁和中度至重度抑郁.
- 评估了匹兹堡睡眠质量指数 (PSQI),时间域,频率域和非线性HRV指数 (波恩卡尔图,近似 (ApEn),DFAα1).
主要成果:
- 在非抑郁和抑郁BC患者组之间观察到时间域,频域,SD1和DFAα1HRV参数和睡眠质量的显著差异.
- SDS和PSQI得分显示与HRV参数的相关性.
结论:
- 在BC患者中,抑郁症的严重程度与心脏自主调节的减弱有关.
- 抑郁症增加与心脏动态复杂性降低和乳腺癌患者睡眠质量降低相关.
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