阻断HIF-1α/糖解轴通过降低ILC2代谢和功能来抑制过敏呼吸道炎症

Xiaogang Zhang1, Jingping Liu2, Xinyao Li3

  • 1Pediatric Intensive Care Unit, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences); Department of Immunology, School of Basic Medical Sciences; Department of Clinical Laboratory, The Third Affiliated Hospital of Southern Medical University, Southern Medical University, Guangzhou, China.

Allergy
|October 27, 2024
PubMed
概括

缺氧诱导因子-1α (HIF-1α) /糖解途径对于过敏性喘中2组先天性淋巴细胞 (ILC2) 激活至关重要. 针对这一轴可能为喘治疗提供新的免疫治疗策略.

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