在社区中患有痴呆症的人处方模式:一个横截面研究
Edward Chun Yin Lau1, Yun-Hee Jeon2, Sarah N Hilmer3
1Faculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.
Australasian journal on ageing
|October 27, 2024
概括
潜在不合适的药物 (PIM),精神药物和多药物在社区居住的痴呆症患者中很常见. 教育和年龄等因素影响药物使用,突出了药物审查的必要性.
科学领域:
- 老年人药理学老年人药理学
- 痴呆症护理 痴呆症护理
- 公共卫生 公共卫生
背景情况:
- 对社区居住的痴呆症患者来说,药物管理至关重要.
- 了解药物使用模式和相关因素对于优化护理至关重要.
- 潜在不合适的药物 (PIM) 和多药在这个人群中构成风险.
研究的目的:
- 为了确定在社区居住的痴呆症患者中药物使用的流行率.
- 识别与特定药物类别和多药学相关的因素.
- 为在痴呆症护理中更安全的药物管理提供未来干预措施的信息.
主要方法:
- 采用澳大利亚悉尼跨学科家庭康复计划 (I-HARP) 的基线数据 (2018-2021) 的横截面研究.
- 包括130名轻度至中度痴呆症患者及其照顾者.
- 药物使用按解剖治疗化学代码进行分类;PIMs按酒标准和澳大利亚清单定义;用于分析的后勤回归.
主要成果:
- 发现PIM (76%) 和多药 (65%) 的高流行率.
- 多药学与精神药物使用 (aOR:5.09) 和PIMs (aOR:17.38) 有意义地相关.
- 高等教育与较低的精神药物使用相关 (aOR:0.33);80岁以上与较少的抗痴呆药物使用相关 (aOR:0.29).
结论:
- 在社区居住的痴呆症患者中,PIM,精神药物和多药物普遍存在.
- 参与者的特征,包括教育和年龄,与药物使用模式有关.
- 需要进一步的研究来评估PIM和多药对该人口健康结果的影响.
更多相关视频
06:52Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
9.7K
04:13Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
Published on: February 8, 2019
6.7K
相关概念视频
Dementia
97
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
97
Drug Therapy
39
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
39
Alzheimer's Disease: Treatment
165
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
165
Prescription, Nonprescription and Orphan Drugs
699
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
699
Drug Dosage Regimen: Overview
3.5K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.5K
Factors Affecting Drug Response: Overview
1.9K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
1.9K
