延迟接种疫苗和减少对疫苗的信心之间是否存在相关性?
Virginia Reverte1, Matilde Zornoza-Moreno1, Yolanda E Molina-Salas2
1Health Prevention and Protection Service, General Directorate of Public Health and Addictions, Murcia, Region of Murcia, Spain.
Human vaccines & immunotherapeutics
|October 27, 2024
概括
麻疹,疹和红疹 (MMR) 疫苗接种计划的延迟与社会人口统计学因素以及父母对疫苗的信心下降有关,特别是在第一剂疫苗接种时. 这些延迟增加了疫情爆发的风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 疫苗接种延迟增加了疫苗可以预防的疾病爆发的风险.
- 父母对疫苗的信心和社会人口统计学因素是延迟免疫计划的潜在因素.
- 疫苗信心指数 (VCI) 使用5分利克特级别来衡量对疫苗的信心.
研究的目的:
- 为了确定与延迟接种麻疹,疹和红疹 (MMR) 疫苗 (第一剂和第二剂) 相关的社会人口统计因素.
- 为了比较推迟与按时的MMR疫苗接种计划的儿童之间的父母对疫苗的信心.
主要方法:
- 在西班牙穆尔西亚地区进行的研究,分析了2019-2020年 (第一剂量) 和2016-2017年 (第二剂量) 的MMR疫苗队列.
- 参与者分为:及时接种疫苗,稍有延迟,中度延迟和高度延迟.
- 数据是通过在线和电话调查问卷收集的,这些问卷是给家长的.
主要成果:
- 对于MMR第一剂,延迟与出生顺序和孩子的智力/运动延迟,父母教育,初级疫苗信息来源和社交网络使用有关.
- 对于MMR第二剂,延迟与儿童的运动/智力延迟以及对兄弟姐妹的照顾责任有关.
- 疫苗信心指数随着第一剂的延迟增加而显著下降,但对第二剂的延迟并没有显著下降.
结论:
- 社会人口统计学因素显著影响了MMR疫苗的延迟,特别是在第一剂时.
- 父母对疫苗的信心与MMR第一剂量计划的延迟有关.
- 了解这些因素对于改善疫苗接种覆盖率和防止疫情爆发至关重要.
相关概念视频
01:51Vaccinations
44.1K
Overview
44.1K
01:24Confidence Coefficient
7.5K
The confidence coefficient is also known as the confidence level or degree of confidence. It is the percent expression for the probability, 1-α, that the confidence interval contains the true population parameter assuming that the confidence interval is obtained after sufficient unbiased sampling; for example, if the CL = 90%, then in 90 out of 100 samples the interval estimate will enclose the true population parameter. Here α is the area under the curve, distributed equally under...
7.5K
01:23Immunological Memory
545
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
545
01:21Confidence Intervals
6.1K
An unbiased point estimate is often insufficient to predict a population estimate, such as population mean or population proportion. In this scenario, a confidence interval is used. A confidence interval is an estimate similar to a sample proportion. However, unlike the point estimate which is a single value, the confidence interval contains a range of values. These values have lower and upper limits, known as confidence limits, and can be designated as L1 and L2, respectively.
A...
A...
6.1K
01:25Confidence Interval for Estimating Population Mean
7.2K
A point estimate of the population mean is obtained from a single sample. Such a point estimate does not represent a population well because it needs to account for variability in the population. Single point estimate can also be biased despite the sample being selected randomly. Thus, a point estimate is often unreliable. A confidence interval is needed to reduce this unreliability.
A confidence interval for the mean is a range of values that provides an estimate of the population mean. As the...
A confidence interval for the mean is a range of values that provides an estimate of the population mean. As the...
7.2K
01:27Confounding in Epidemiological Studies
145
Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
145