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Updated: Jun 9, 2025

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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通过PPM1G介导的TBL1XmRNA剪接促进肝细胞癌中的细胞迁移

Liling Hu1, Xinyu Shi1, Xiaoyi Yuan1

  • 1MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.

Cancer science
|October 27, 2024
PubMed
概括

这项研究确定PPM1G是肝细胞癌 (HCC) 转移的生物标志物. 它揭示了PPM1G调节TBL1X-S拼接变体,通过增强ZEB1活性和加速上皮层-介质细胞过渡 (EMT) 来促进瘤扩散.

关键词:
在HCC中,HCC是HCC.这是一个PPM1G.这是一个TBL1XX.另一个替代拼接方法是拼接.转移 转移 转移 转移

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