电心电图分析,以评估心力衰竭的风险与保存的喷射分数:一个深度学习模型
Zheng Gao1, Yuqing Yang1, Zhiqiang Yang2,3
1Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
ESC heart failure
|October 28, 2024
概括
一个深度学习模型 (DLM) 有效地选使用心电图 (ECG) 的心力衰竭与保存喷射率 (HFpEF) 风险. 这种具有成本效益的工具有助于早期检测和改善HFpEF的管理.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医学诊断 医学诊断 医学诊断
背景情况:
- 由于缺乏有效的查方法,心力衰竭与保存的喷射分数 (HFpEF) 构成了重大的临床挑战.
- 早期识别HFpEF对于及时干预和改善患者结果至关重要.
研究的目的:
- 开发和验证一个深度学习模型 (DLM) 以准确和成本效益的选HFpEF风险.
- 通过使用心电图 (ECG) 评估DLM的性能,以识别高风险HFpEF的个体.
主要方法:
- 一个卷积神经网络长期短期记忆 (CNN-LSTM) DLM被开发和训练在从队列A (n=238) 的心电图数据.
- HFpEF风险是由左心室末端透气压 (LVEDP) 和临床症状来定义的,LVEDP通过侵入性导管测量.
- 在一个独立的数据集,B队列 (n=117) 上,对DLM进行了前性验证.
主要成果:
- 在培训 (A队列) 和验证 (B队列) 队列中,DLM在HFpEF风险评估中实现了78%的准确性.
- 在B组中,DLM表现为71.9%的特异性和71.7%的敏感性.
- 与低风险组相比,DLM识别的高风险HFpEF组显示出糖尿病和肥胖的更高患病率,以及较低的CCB使用率,与BNP和E/E"等传统标志物不同.
结论:
- 开发的DLM提供了一种准确且具有成本效益的方法,用于使用ECG选高风险.
- 这种人工智能驱动的方法有可能促进早期检测,并增强HFpEF患者的临床管理策略.
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