相关实验视频
Updated: Jul 21, 2026

08:08
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
Published on: September 22, 2017
10.9K
在脉动和非脉动的儿科模拟电路中评估体外膜氧化器管
Lorenzo Ferrari1, Maris Bartkevics2, Hansjörg Jenni2
1ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.
Artificial organs
|October 28, 2024
概括
脉冲性流量条件为体外膜氧化 (ECMO) 管提供了更多的生理测试,需要更低的速度,从而减少流量增加. 非脉动的流量导致更高的压力和总血液动力学能量.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医疗器械测试 医疗器械测试
背景情况:
- 评估动脉和静脉管的血液动力学性能对于儿科外体膜氧化 (ECMO) 是至关重要的.
- 了解不同流量条件下的性能 (脉冲性与非脉冲性) 对于患者安全和设备选择至关重要.
研究的目的:
- 评估各种儿科ECMO小管的血液动力学性能.
- 在模拟电路中,在脉动和非脉动的流量条件下比较管性能.
主要方法:
- 使用了符合标准的儿科ECMO模拟电路,配有氧化器,和压力传感器.
- 模拟儿科条件使用验证的左心模拟循环,以120bpm的脉动性流量和通过滚筒的非脉动性流量.
- 在不同流速下测试了多个动脉和静脉管的大小.
主要成果:
- 与非脉动性流量相比,脉动性流量条件需要更低的ECMO速度,并诱导较少的流量增加.
- 非脉动性流动导致了较高的大动脉和动脉压力,以及更大的总血液动力学能量.
- 在脉动和非脉动条件之间,没有观察到压力下降或M数的显著差异.
结论:
- 非脉动性ECMO条件导致更高的系统压力,可能提供更大的患者支持.
- 脉冲性测试条件更准确地反映了生理状态,并被推用于ECMO设备评估.
- 管压力梯度和M数是独立于测试的流量条件.
相关概念视频
Oxygen Delivering System I: Nasal Cannula and Face Mask
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Oxygen Delivering System III: Tracheostomy and T-piece
Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Mechanical Ventilation II: Invasive Ventilation
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Noninvasive Positive-Pressure Ventilation (NIPPV)

