对眼皮表面和眼功能眼镜治疗的影响:对白内障切除术和抗白内障滴剂的比较
Abdussamet Mermer1, Özer Dursun2, Öznur Bucak3
1Şanlıurfa Viranşehir State Hospital, Clinic of Ophthalmology, Şanlıurfa, Türkiye.
Turkish journal of ophthalmology
|October 28, 2024
概括
青光眼的治疗方法,包括抗青光眼药物和使用米托米C的轨道切除手术,同样影响眼睛表面疾病 (OSD). 两种治疗都没有在OSD发病率上表现出优势,这表明对功能和眼睛健康的影响相似.
科学领域:
- 眼科医生 眼科 眼科
- 眼睛表面疾病 眼睛表面疾病
- 视光眼的管理 视光眼的管理
背景情况:
- 青光眼的管理通常涉及局部药物或外科干预,如带切除术.
- 这两种治疗方式都可能影响眼睛表面.
- 了解对眼表面疾病 (OSD) 的比较影响对于患者护理至关重要.
研究的目的:
- 为了比较眼功能和OSD发现,在一个眼睛用抗眼药物治疗的玻璃眼患者和在另一个眼睛用米托米辛C (MMC) 进行的轨道切除手术.
- 评估每个治疗方式引起的OSD程度.
主要方法:
- 研究了一组19名青光眼患者 (38只眼睛) 的队列,这些患者之前曾经接受过MMC的轨道切除术.
- 一只眼睛接受了轨道眼切除术 (至少6个月前,没有药物治疗),而另一只眼睛接受了抗葡萄糖瘤药物治疗.
- 包括一个由20名健康个体组成的对照组. 进行了眼分离时间 (BUT),光素染色,希尔默II测试和结膜印象细胞学.
主要成果:
- 与健康对照组相比,青光眼患者在BUT,角膜/结膜染色,希尔默II测试和纳尔逊分期方面表现出统计学上显著的差异 (p=0.05).
- 虽然在统计学上并不显著,但随着术后时间的延长,BUT,希尔默II测试,点点染色和纳尔逊分期的改善被观察到.
- 两个治疗组都表现出OSD发现.
结论:
- 抗玻璃眼癌药物和使用MMC进行的轨道切除手术在玻璃眼癌患者中诱导OSD的程度相似.
- 在使用MMC和抗白内障眼滴的轨道眼切除术之间,在OSD发病率上没有发现显著的优势.
- 这两种治疗策略对眼表面疾病的发展具有相似的风险.
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