从婴儿期到童年期的胆管和精神运动发育:日本环境和儿童研究
Karri Silventoinen1,2, Chika Honda1, Rie Tomizawa1
1Center for Twin Research, Osaka University Graduate School of Medicine, Osaka, Japan.
概括
双胞胎与单生子相比,在早期的精神运动发育中表现出延迟. 这种发育差距受到诸如出生体重等因素的影响,缩小了,但持续到三岁,并非单双胞胎的特点.
科学领域:
- 发展心理学是发展心理学.
- 儿科 儿科 儿科
- 周围生理学 周围生理学
背景情况:
- 双胞胎通常与单身双胞胎相比,表现出发育上的差异.
- 胆管性对双胞胎发育轨迹的影响尚不清楚.
研究的目的:
- 为了比较单子,单 (MC) 双胞胎和双 (DC) 双胞胎的早期精神运动发育.
- 调查胆管性对双胞胎发育迟缓的影响.
主要方法:
- 使用来自日本环境和儿童研究 (JECS) 的数据进行长度研究.
- 包括98,042个单身,577个MC双胞胎和1051个DC双胞胎.
- 用年龄和阶段问卷 (ASQ-3) 评估6个时间点的精神运动发展,从6个月到3年.
- 通过超声波和产后检查确定胆管性.
- 使用线性回归模型进行统计分析.
主要成果:
- 双胞胎在婴儿时期与单生双胞胎相比,在所有精神运动发育领域都表现出延迟.
- 双胞胎和单胞胎之间的发育差距随着时间的推移而减少,但在3岁时仍然明显.
- 较低的出生体重和较早的妊娠年龄占双胞胎单身发育差异的一半以上.
- 单胆双胞胎的发育比双胆双胞胎的发育稍有延迟,尽管与双胞胎单胆双胞胎的整体差距相比,这种差异很小.
结论:
- 双胞胎在早期的精神运动发育中相对于单生双胞胎而言会出现延迟.
- 这些延迟受到诸如出生体重和早产等因素的显著影响.
- 在双胞胎中观察到的发育滞后并非特定于单胞胎双胞胎.
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